It is obvious that 'Christ Jesus' is an interpolation or insertion.
That there had been an outburst of persecution among the believers in Rome is also obvious. The religion of these folk had nothing to do with an imaginary Jesus. It had a Jewish origin among the prophets. It was routed in the spirit of God indwelling each individual from birth. The person writing was Agrippa I and the person being addressed was the emperor Nero.
The spirit was thought to have passed down through mothers. The spirit sustained life. It could be fanned into 'flame'. Agrippina the Elder is regarded in ancient and modern historical sources as a Roman Matron with a reputation as a great woman, who had an excellent character and had outstanding Roman morals. She was a dedicated, supporting wife and mother who looked out for the interests of her children and the future of her family.
She would have been a good example to her daughter Agrippina the Younger.
The deaths of a number of people were linked to that persecution. I include the deaths of Nero, his wife Poppea, his mother Agrippina, Seneca, Burrus and Epaphroditus. I can only think that they were murdered by those opposed to the introduction of Jewish prophetic religion with its indwelling of the spirit of God. The Church Fathers created unbelievable, fabricated accounts of their deaths. This was a persecution of CHRISTIANOS, a latin name found at Pompeii visited by the elite Roman rulers. The CHRISTIANOS (anointed ones) were in fact called atheists because they didn't worship a physical god, an idol, but worshipped in the Spirit of God, as in Acts.
[You know very well in how many ways he helped me in Rome.]